Intermediates

S.No.

API

INTERMEDIATE NAME

CAS No.

1.

BUMATENIDE

5-aminosulfonyl-4-chloro-3-nitrobenzoic acid

[22892-96-2]

2.

BENDAMUSTINE

4-(6-(bis(2-hydroxyethyl)amino)-1-methyl1H-benzo[d]imidazol-2-yl)butanoic acid

109882-30-6

3.

CABERGOLINE

6-(2-Propenyl)-ergoline-8-carboxylic acid

[81409-74-7]

4.

CANAGLIFLOZIN

2,3,4,6-Tetrakis-O-(trimethylsilyl)D-glocono 1,5-lactone

[32384-65-9]

5-Bromo-2-Methyl Benzoic Acid

79669-49-1

2-(5-bromo-2-methylbenzyl)-5-(4-fluorophenyl) thiophene

1030825-20-7

5.

DABIGATRAN

N-(4-cyanophenyl)glycine

[42288-26-6]

Ethyl-3-Pyridin-2-ylamino propanate

[103041-38-9]

3-[(3-Amino-4-Methylamino-Benzoyl)-Pyridin-2-Yl-Amino]-Propionic Acid Ethyl Ester

[212322-56-0]

6.

DASATINIB

2-Amino-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide

[302964-24-5]

7.

DOLUTEGRAVIR

3-Benzyloxy-5-bromo-2-methylpyridin-4-ol

[906657-86-1]

(R)-3-Amino-Butan-1-ol

[61477-40-5]

8.

EZOGABINE

(4-Amino-2-nitrophenyl)carbamic acid ethyl ester

[73875-87-1]

[4-[(4-fluorophenyl) methyl)amino]--2-nitrophenyl]carbamic acid ethyl ester

[150812-23-0]

3,4-Dichloro-1,2,5-thiadiazole

5728-20-1

9.

ETRAVIRINE

4[(4,6-dichloropyrimidin-2-yl)amino]benzonitrile

[329187-59-9]

10.

FESOTERODINE

3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-(phenylmethoxy)benzoic acid methyl ester

[156755-35-0]

11.

FINGOLIMOD

2-(4-Octylphenyl)-1-iodoethane

[162358-07-8]

Diethyl acetamidomalonate

[1068-90-2]

12.

GENTISIC ACID

2,5-Dihydroxybenzoic Acid

490-79-9

13.

GEFITINIB

3,4-Dihydro-7-methoxy-4-oxoquinazolin-6-yl acetate

[179688-53-0]

14.

LEVOTHYROXINE /LIOTHYRONINE

3,5-Diiodo-L-thyronine

[1041-01-6]

3,5-Diiodo-L-Tyrosine Dihydrate

Bis(P-Anisyl)Iodonium Bromide

19231-06-2

Bis(p-anisyl)iodonium iodide

6293-71-6

15.

LINEZOLID

3-[3-Fluoro-4-(4-morpholinyl)phenyl]-5-

[[(methylsulfonyl)oxy]methyl]-2-oxazolidinone

[858344-36-2]

16.

LENALIDOMIDE

2-Bromomethyl-3-nitro-benzoic acid methyl ester

[98475-07-1]

3 Amino-piperidine-2,6-dione hydrochloride

[24666-56-6]

3-(4-Nitro-1-oxo-1, 3-dihydro-isoindol-2yl)-piperidine-2,6-dione

[827026-45-9]

17.

LETROZOLE

4-(1H-1,2,4-Triazol-1-ylmethyl)benzonitrile

[112809-25-3]

18.

MISOPROSTOL

methyl 7-(5-oxo-3-((triethylsilyl)oxy)cyclopent-1-en-1-yl) heptanoate

[112713-92-5]

19.

NILOTINIB

1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one

[55314-16-4]

3-[(Aminoiminomethyl)amino]-4-methylbenzoic acid ethyl ester mononitrate

[641569-96-2]

20.

OLMESARTAN

Ethyl 4-(1-hydroxy-1-methylethyl)-2-propyl-1H-imidazole-5-carboxylate

[144689-93-0]

21.

PRASUGREL

2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone

[204205-33-4]

5,6,7,7a-Tetrahydrothieno[3,2-c]pyridine-2(4H)-one hydrochloride

[115473-15-9]

22.

PALIPERIDONE

3-(2-Chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one

[130049-82-0]

23.

RANOLAZINE

N-(2,6-Diphenylmethyl)-1-piperazine acetylamine

[5294-61-1]

24.

RIVORAXABIN

4-Phenylmorpholin-3-one

29518-11-4

4-(4-aminophenyl)morpholin-3-one

438056-69-0

4-[4-[(5S)-5-Phthalimidomethyl-2-oxo-3-

oxazolidinyl]phenyl]-3-morpholinone

446292-08-6

4-[4-[(5S)-5-(Aminomethyl)-2-oxo-3-

oxazolidinyl]phenyl]-3-morpholinone HCl

898543-06-1

25.

SULINDAC

Sulindac sulphide

[32004-67-4]

26.

VALGANCYCLOVIR

Ganciclovir Mono acetate

[88110-89-8]

N-carbobenzoyloxy-L-valinyl-Ganciclovir

[194154-40-0]

27.

ZOLPIDEM

6-Methyl-2- (-4-methylphenyl)-imidazo [1,2-a] pyridine-3-acetic acid

[189005-44-5]

28.

ZOPICLONE

2,3-pyrazine dicarboxlic acid anhydride

[4744-50-7]

6-(5-Chloro-2-pyridyl)-6,7-dihydro-7-hydroxy-5H-pyrrolo[3,4-b]pyrazin-5-one

[43200-81-3]

29.

Specialty chemical

Potassium Trimethyl silonalate

10519-96-7

30.

Specialty Chemical

Sodium Trimethyl silonalate

31.

Specialty Chemical

4-Penten-1-amine, 2,2-di-2-propen-1-y (DAPA)

928836-00-4

32.

Specialty Chemical

Nitraso methyl urea

684-93-5

33.

Specialty Chemical

2,7-Diiodofluorene-9-carboxyli acid

74993-62-7

34.

Specialty chemical

2-[4-(1-Methyl-1-phenyl-ethyl)-phenoxycarbonyloxy]-benzoic acid phenyl ester

405553-18-6

35.

Specialty Chemical

Pentamethyl sulfide

1613-51-0

36.

7-Aza indole

[271-63-6]

37.

2-Bromo-5-methoxy-benzaldehyde

[7507-86-0]

38.

Sucrose Octasulfate Potassium

73264-44-5

39.

Tetraphenyl phosphonium phenolate